Dr Kiran Bala1, Mrs. Savita Shokeen1, Dr. Namrata Makkar1, Mr. Pooran Mahendra1, Dr. Hitender Gautam1, Dr. Seema Sood1, Dr. Bimal Kumar Das1
1All India Institute Of Medical Sciences, New Delhi, India, 2All India Institute of Medical Sciences, New Delhi, India, 3All India Institute of Medical Sciences, New Delhi, India, 4All India Institute of Medical Sciences, New Delhi, India, 5All India Institute of Medical Sciences, New Delhi, India, 6All India Institute of Medical Sciences, New Delhi, India, 7All India Institute of Medical Sciences, New Delhi, India
Biography:
Dr. Kiran Bala is Additional Professor in Department of Microbiology at All India Institute of Medical Sciences, New Delhi. She has experience of 12 years in hospital infection control. She is looking after National center of ageing and Hospital associated Infections in Pulmonary medicine.
Abstract:
Introduction
Ventilator-associated pneumonia infections (VAPs) are one of the device-associated infections acquired in a hospital which is difficult to manage. Elderly patients are highly susceptible to hospital acquired infections (HAI; VAP, CLABSI, CAUTI,) as devices are life saving measures often required for their management.
Aim
This study focuses on the profile of VAP, the organism profile with antibiotic susceptibility patterns, and the clinical outcomes in the ICUs of a critically ill ageing patients in geriatric center.
Methodology
A retrospective analysis of prospective surveillance data of patients in ICUs was done over a period of ten months (June 2024-March 2025) in the intensive care unit of National centre of ageing, AIIMS New Delhi. A modified NHSN definition of VAP was used. Microbiological processing and antibiotic susceptibility profile was done based on standard guidelines. Clinical outcomes were considered for analysis.
Results
A total of 513 patients were included in the study, accounting for 2259 patient days and 1,396 ventilator days (VD). Among 546 patients, 51 episodes of VAP were recorded, giving a VAP rate of 25.2/1,000 ventilator days. The average length of stay (LOS) of patients was 25.9 days. There was a significant relationship between VD and the development of VAP. Gram-negative organisms (98%) dominated the pathogen profile. Among them most common were Acinetobacter baumani (47%), Klebsiella pneumoniae (39.2%). The crude mortality was 35.1%.
Conclusions
Surveillance of VAP with analysis of the organisms and the antibiotic susceptibility trend will help improve infection prevention practices and antibiotic stewardship programs in local hospital settings.